منابع مشابه
STUDIES ON STREPTOMYCIN VI. : The Effect of Streptomycin on the Metabolism of Multiplying Bacteria.
In a previous study the authors (Henry et al., 1948) reported on some of the effects of streptomycin (SM) on the metabolism of resting cells of Staphylococcus aureus, BaciUus cereus, and Shigella sonnei. It was found that SM inhibited the oxidation of certain carbohydrates and carbohydrate intermediates by susceptible strains of these organisms, but had no inhibitory effect on resistant strains...
متن کاملCounter-current distribution studies on streptomycin; the tautomerism of streptomycin.
The simplicity and reproducibility which characterize the conversion of streptomycin to malt01 (1) by heating in dilute alkali have made this reaction the basis of a frequently used analytical method for streptomycin (2). When used in these laboratories as a method of assaying streptomycin preparations, however, the malt01 reaction consistently gave lower yields per unit of potency with pure st...
متن کاملStudies on Digitalis VI
T IS undisputed that the administration of digitalis to patients with many forms of congestive heart failure results in an improvement in both the clinical state and in the abnormal circulatory dynamics that are characteristic of heart failure.'-6 The effects of digitalis in subjects without heart failure are less well defined. Although some glycosides augment the contractile force of nonfailin...
متن کاملEnzymic Studies on the Biosynthesis of Streptomycin
1; Heat extracts of mature mycelia of streptomycin-producing strains of Sfreptomyces contain two compounds which, when incubated with arginine-guanidino-‘*C plus a crude enzyme preparation from S. griseus ATCC 12475 containing a&nine: X amidinotrausferase, give products detected as radioactive Peaks I and II. Heat extracts from S. bluensis var. bluensis, which synthesizes bluensomycin, a monogu...
متن کاملThe action of streptomycin. VI. A new metabolic intermediate.
In attempting to explain the results obtained when certain strains of Escherichia coli were treated with streptomycin, a reaction between pyruvate and oxalacetate was proposed as the sensitive reaction. The action of streptomycin on this reaction was regarded as being related to its action in inhibiting the organism since only antibiotically active forms of streptomycin were inhibitory and comp...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1949
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.57.4.447-451.1949